Evangelos Michelakis: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

Sutendra, Gopinath, Kinnaird, Adam, Dromparis, Peter, Paulin, Roxane, Stenson, Trevor H., Haromy, Alois, Hashimoto, Kyoko, Zhang, Nancy, Flaim, Eric, Michelakis, Evangelos D.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.08 MB

english, 2014

2

Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

Paulin, Roxane, Dromparis, Peter, Sutendra, Gopinath, Gurtu, Vikram, Zervopoulos, Sotirios, Bowers, Lyndsay, Haromy, Alois, Webster, Linda, Provencher, Steeve, Bonnet, Sebastien, Michelakis, Evangelos

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 3.79 MB

english, 2014

3

Acute Hemodynamic Effects of Single-Dose Sildenafil When Added to Established Bosentan Therapy in Patients With Pulmonary Arterial Hypertension: Results of the COMPASS-1 Study

Gruenig, Ekkehard, Michelakis, Evangelos, Vachiéry, Jean-Luc, Vizza, Carmine Dario, Meyer, F. Joachim, Doelberg, Martin, Bach, Doris, Dingemanse, Jasper, Galiè, Nazzareno

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 252 KB

english, 2009

4

Metabolic control of epigenetics in cancer

Kinnaird, Adam, Zhao, Steven, Wellen, Kathryn E., Michelakis, Evangelos D.

Journal:

Nature Reviews Cancer

Year:

2016

Language:

english

File:

PDF, 583 KB

english, 2016

5

Calcium channels in smooth muscle cells from cerebral precapillary arterioles activate at more negative potentials than those from basilar artery

Evangelos Michelakis, Kirti Tewari, J. Marc Simard

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1994

Language:

english

File:

PDF, 323 KB

english, 1994

6

The role of mitochondria in pulmonary vascular remodeling

Peter Dromparis, Gopinath Sutendra, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

7

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Gopinath Sutendra, Peter Dromparis, Sébastien Bonnet, Alois Haromy, Michael S. McMurtry, R. Chris Bleackley, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

8

The Role of the NO Axis and its Therapeutic Implications in Pulmonary Arterial Hypertension

Evangelos D. Michelakis

Journal:

Heart Failure Reviews

Year:

2003

Language:

english

File:

PDF, 446 KB

english, 2003

9

The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary Vasoconstriction and Pulmonary Arterial Hypertension

ROHIT MOUDGIL, EVANGELOS D. MICHELAKIS, STEPHEN L. ARCHER

Journal:

Microcirculation

Year:

2006

Language:

english

File:

PDF, 1.58 MB

english, 2006

10

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

Jayan Nagendran, Vikram Gurtu, David Z. Fu, Jason R.B. Dyck, Al Haromy, David B. Ross, Ivan M. Rebeyka, Evangelos D. Michelakis

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2008

Language:

english

File:

PDF, 1.37 MB

english, 2008

11

Anorectic drugs and vascular disease:: The role of voltage-gated K+ channels

Evangelos Michelakis

Journal:

Vascular Pharmacology

Year:

2002

Language:

english

File:

PDF, 249 KB

english, 2002

12

Phosphodiesterase Type 5 Inhibitors for Pulmonary Arterial Hypertension

Archer, Stephen L., Michelakis, Evangelos D.

Journal:

Boston Medical and Surgical Journal

Year:

2009

Language:

english

File:

PDF, 543 KB

english, 2009

13

Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells

Evangelos D. Michelakis, Bernard Thébaud, E. Kenneth Weir, Stephen L. Archer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2004

Language:

english

File:

PDF, 831 KB

english, 2004

14

Diversity of mitochondria in vascular oxygen sensing

Evangelos Michelakis, Stephen Archer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001

15

A pulmonary vascular redox O2 sensor

Stephen Archer, Evangelos Michelakis

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

16

The opposing effects of hypoxia on pulmonary versus renal arteries are regulated by a mitochondria-based O2 sensor

Evangelos Michelakis, Ali Nsair, Xsi-Cheng Wu, Kyoko Hashimoto, Stephen Archer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 171 KB

english, 2001

17

The proximal mitochondrial electron transport chain regulates O2 sensing in the human ductus arteriosus

Bernard Thebaut, Evangelos Michelakis, Ali Nsair, Ivan Rebeyka

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

18

Voltage-gated potassium channels in human ductus arteriosus

Evangelos Michelakis, Ivan Rebeyka, Jane Bateson, Peter Olley, Lakshmi Puttagunta, Stephen Archer

Journal:

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

19

Mitochondria in Vascular Health and Disease

Dromparis, Peter, Michelakis, Evangelos D.

Journal:

Annual Review of Physiology

Year:

2013

Language:

english

File:

PDF, 1.80 MB

english, 2013

20

G-protein-coupled receptors and pulmonary arterial hypertension (PAH)

Roxane Paulin, Evangelos Michelakis

Journal:

Drug Discovery Today: Disease Models

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

21

297 DICHLOROACETATE IS A NOVEL THERAPY FOR RENAL CELL CARCINOMA

Kinnaird, Adam, Dromparis, Peter, Haromy, Alois, Bowers, Lyndsay, Hashimoto, Kyoko, Sutendra, Gopinath, Michelakis, Evangelos

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

22

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

Paul M. Hassoun, Luc Mouthon, Joan A. Barberà, Saadia Eddahibi, Sonia C. Flores, Friedrich Grimminger, Peter Lloyd Jones, Michael L. Maitland, Evangelos D. Michelakis, Nicholas W. Morrell, John H. New

Journal:

Journal of the American College of Cardiology

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

23

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension

Evangelos D. Michelakis, Wayne Tymchak, Dale Lien, Linda DaSilva, Kyoko Hashimoto, Stephen L. Archer

Journal:

Journal of the American College of Cardiology

Year:

2002

Language:

english

File:

PDF, 163 KB

english, 2002

24

Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

Tuder, Rubin M., Archer, Stephen L., Dorfmüller, Peter, Erzurum, Serpil C., Guignabert, Christophe, Michelakis, Evangelos, Rabinovitch, Marlene, Schermuly, Ralph, Stenmark, Kurt R., Morrell, Nicholas

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 602 KB

english, 2013

25

Reduced native right ventricular T1in Anderson-Fabry disease as compared to patients with pulmonary hypertension

Pagano, Joseph J, Chow, Kelvin, Khan, Aneal, Michelakis, Evangelos, Paterson, Ian, Oudit, Gavin Y, Thompson, Richard B

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

26

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells

Dromparis, Peter, Sutendra, Gopinath, Paulin, Roxane, Proctor, Spencer, Michelakis, Evangelos D., McMurtry, M. Sean

Journal:

Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 827 KB

english, 2014

27

THE PATHOBIOLOGY OF PULMONARY HYPERTENSION

Michelakis, Evangelos D., Weir, E. Kenneth

Journal:

Clinics in Chest Medicine

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001

28

The Metabolic Basis of Pulmonary Arterial Hypertension

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 3.03 MB

english, 2014

29

O2Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Stephen L. Archer, Helen L. Reeve, Evangelos Michelakis, Lakshmi Puttagunta, Ross Waite, Daniel P. Nelson, Mary C. Dinauer and E. Kenneth Weir

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.32 MB

english, 1999

30

Riociguat for HF with Pulmonary Hypertension (PH): Post-hoc Analysis of LEPHT by Baseline Pulmonary Vascular Resistance (PVR) and Pulmonary Vascular Gradient (PVG)

Bonderman, Diana, Ghio, Stefano, Felix, Stephan B., Ghofrani, Hossein-Ardeschir, Michelakis, Evangelos, Mitrovic, Veselin, Oudiz, Ronald J., Boateng, Francis, Roessig, Lothar, Semigran, Marc J.

Journal:

Journal of Cardiac Failure

Year:

2014

Language:

english

File:

PDF, 127 KB

english, 2014

31

New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy

Haddad, Francois, Ashley, Euan, Michelakis, Evangelos D

Journal:

Current Opinion in Cardiology

Year:

2010

Language:

english

File:

PDF, 442 KB

english, 2010

32

Left ventricular systolic dysfunction associated with pulmonary hypertension riociguat trial (LEPHT): rationale and design

Ghio, Stefano, Bonderman, Diana, Felix, Stephan B., Ghofrani, Hossein A., Michelakis, Evangelos D., Mitrovic, Veselin, Oudiz, Ronald J., Frey, Reiner, Roessig, Lothar, Semigran, Marc J.

Journal:

European Journal of Heart Failure

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

33

Metabolic modulation of cancer: a new frontier with great translational potential

Kinnaird, Adam, Michelakis, Evangelos D.

Journal:

Journal of Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

34

A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors

Chu, Quincy Siu-Chung, Sangha, Randeep, Spratlin, Jennifer, J. Vos, Larissa, Mackey, John R., McEwan, Alexander J. B., Venner, Peter, Michelakis, Evangelos D.

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 475 KB

english, 2015

35

Critical Role of the Axonal Guidance Cue EphrinB2 in Lung Growth, Angiogenesis, and Repair

Vadivel, Arul, van Haaften, Tim, Alphonse, Rajesh S., Rey-Parra, Gloria-Juliana, Ionescu, Lavinia, Haromy, Al, Eaton, Farah, Michelakis, Evangelos, Thébaud, Bernard

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 2.29 MB

english, 2012

36

Emerging Therapies and Future Directions in Pulmonary Arterial Hypertension

Gurtu, Vikram, Michelakis, Evangelos D.

Journal:

Canadian Journal of Cardiology

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015

37

Use of Sildenafil for Safe Improvement of Erectile Function and Quality of Life in Men With New York Heart Association Classes II and III Congestive Heart Failure

Webster, Linda J., Michelakis, Evangelos D., Davis, Terry, Archer, Stephen L.

Journal:

Archives of Internal Medicine

Year:

2004

Language:

english

File:

PDF, 111 KB

english, 2004

38

Updating clinical endpoint definitions

Hassoun, PaulM, Nikkho, Sylvia, Rosenzweig, ErikaB, Moreschi, Gail, Lawrence, John, Teeter, John, Meier, Christian, Ghofrani, ArdeshirH, Minai, Omar, Rinaldi, Paula, Michelakis, Evangelos, Oudiz, Rona

Journal:

Pulmonary Circulation

Year:

2013

Language:

english

File:

PDF, 763 KB

english, 2013

39

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Frontiers in Oncology

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

40

Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus

Thébaud, Bernard, Wu, Xi-Chen, Kajimoto, Hidemi, Bonnet, Sandra, Hashimoto, Kyoko, Michelakis, Evangelos D, Archer, Stephen L

Journal:

Pediatric Research

Year:

2008

File:

PDF, 699 KB

2008

41

Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus

Thébaud, Bernard, Wu, Xi-Chen, Kajimoto, Hidemi, Bonnet, Sandra, Hashimoto, Kyoko, Michelakis, Evangelos D, Archer, Stephen L

Journal:

Pediatric Research

Year:

2008

Language:

english

File:

PDF, 699 KB

english, 2008

42

Sildenafil Reverses O2 Constriction of the Rabbit Ductus Arteriosus by Inhibiting Type 5 Phosphodiesterase and Activating BKCa Channels

Thébaud, Bernard, Michelakis, Evangelos, Wu, Xi-Chen, Harry, Gwyneth, Hashimoto, Kyoko, Archer, Stephen L

Journal:

Pediatric Research

Year:

2002

Language:

english

File:

PDF, 1.24 MB

english, 2002

43

The Role of Doppler Echocardiography in Pulmonary Artery Hypertension

Paterson, Ian, Michelakis, Evangelos D.

Journal:

Year:

2011

Language:

english

File:

PDF, 944 KB

english, 2011

44

Pulmonary Vasoconstriction, Oxygen Sensing, and the Role of Ion Channels

Weir, E. Kenneth, Reeve, Helen L., Peterson, Douglas A., Michelakis, Evangelos D., Nelson, Daniel P., Archer, Stephen L.

Journal:

Year:

1998

Language:

english

File:

PDF, 3.38 MB

english, 1998

45

Cell-Based Gene Therapy in Pulmonary Arterial Hypertension: Table.

Gurtu, Vikram, Michelakis, Evangelos

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 470 KB

english, 2015

46

A Global Pulmonary Arterial Hypertension Registry: Is It Needed? Is It Feasible?

Gomberg-Maitland, Mardi, Michelakis, Evangelos D.

Journal:

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

47

PD33-11 METABOLIC MODULATION WITH DICHLOROACETATE REVERSES THE WARBURG EFFECT AND REDUCES THE GROWTH OF CLEAR CELL RENAL CELL CARCINOMA IN VITRO AND IN VIVO

Kinnaird, Adam, Dromparis, Peter, Paulin, Roxane, Saleme, Bruno, Stenson, Trevor, Pink, Desmond, Lewis, John, Michelakis, Evangelos

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

48

ACUTE HEMODYNAMIC EFFECT OF SILDENAFIL IN COMPARISON WITH INHALED NITRIC OXIDE IN PATIENTS RECEIVING BOSENTAN THERAPY FOR PULMONARY ARTERIAL HYPERTENSION

Galie, Nazzareno, Michelakis, Evangelos, Vachiery, Jean-Luc, Vizza, Carmine Dario, Meyer, F.J., Gruenig, Ekkehard

Journal:

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

49

MP85-01 MYOCYTE ENHANCER FACTOR 2A (MEF2A) IS UP-REGULATED IN CLEAR CELL RENAL CELL CARCINOMA

Kinnaird, Adam, Saleme, Bruno, Gurtu, Vikram, Zervopoulos, Sotirios, Boukouris, Aristeidis, Haromy, Alois, Stenson, Trevor, Watson, Kristalee, Dromparis, Peter, Michelakis, Evangelos

Journal:

The Journal of Urology

Year:

2016

Language:

english

File:

PDF, 37 KB

english, 2016

50

F2-Isoprostanes

Dromparis, Peter, Michelakis, Evangelos D.

Journal:

Year:

2012

Language:

english

File:

PDF, 1020 KB

english, 2012